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The reasons
for choosing
Suplasyn 2ml
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High degree of patient satisfaction
Improvement of
daily activities (1)

> 80% of improvement of pain (VAS scores) (2)

Significant improvement of all functional criteria (1)

Significant improvement of:
Extension ability (1)
Flexion range (1)
Very good
safety profile

Extremely low rate of adverse events
(< 2% adverse events observed)**

> 80% of improvement of pain (VAS scores) (2)

Suplasyn® can be efficient from the 1st injection SERIES FOR UP TO 6 MONTHS IN THE MAJORITY OF PATIENTS

Primary efficacy outcome:

Primary efficacy outcome
improvement at first series
improvement at second series
Significant improvement of pain on walking
Significant improvement of all functional criteria (1)
All functional criteria significantly improved
Mean Knee function score (0-10)
Mean Knee function score
morning stiffness
rest stiffness
difficulty walking on flat surface
difficulty climbing stairs
4,507
4,507
4,487
4,494
Diagnostic visit
Follow up visit (30 days)
*p<0.001
  • SUPLASYN® can be efficient from the 1st INJECTION SERIES for up to 6 MONTHS in the majority of patients *** (2)
  • Up to 6 MONTHS clinical effect on pain and functionality *** (2)
  • OPTIMUM MOLECULAR Weight: optimum stimulation of endogenous Hyaluronic
    Acid synthesis & easy access to diseased tissue (3)
  • EASY for doctors to inject (low viscosity)
  • Very good SAFETY ** (1,2)
Suplasyn 2ml

* 4519 patients suffering from osteoarthritis of the knee were included in this study (2011). Subjective sensation of improvement of doctors (n=4,499) and patients (n=4,505) was evaluated.
** Post-marketing surveillance report
*** This depends on patient's individual response

1. Gydek A et al. ¨Efficacy and safety of intra-articular use of Hyaluronic acid (Suplasyn) in the treatment of knee osteoarthritis¨ Przegl Lek. 2011;68(6) 307-10.
2. Petrella R J: Hyaluronic acid for the treatment of knee osteoarthritis: Long-term outcomes from a naturalistic primary care experience. Am J Phys Med Rehabil 2OO5;84:287- 283.
3. Maheu E., Rannou F., Reginster J. Y., Efficacy and safety of hyaluronic acid in the management of osteoarthritis: Evidence from real-life setting trials and surveys. Semin Arthritis Rheum 45, S28-33 (2016).

Injection of
the shoulder
Injection
of the hip
Injection of the
knee inflexion
Injection of the
knee extended
Injection of<br>the shoulder Injection<br>of the jaw
Injection<br>of the hand Injection<br>of the hip
Injection of the<br>knee inflexion Injection of the<br>knee extended
Injection techniques in synovial joints
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